Sulfur mustard vapor effects on differentiated human lung cells
نویسندگان
چکیده
منابع مشابه
Inflammatory effects of inhaled sulfur mustard in rat lung.
Inhalation of sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung damage, is a significant threat to both military and civilian populations. The mechanisms mediating its cytotoxic effects are unknown and were investigated in the present studies. Male rats Crl:CD(SD) were anesthetized, and then intratracheally intubated and exposed to 0.7-1.4mg/kg SM by vapor inhalation....
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Sulfur Mustard (SM) is a potent toxic alkylating agent that has been used as a chemical warfare gas during the World War I and in the Iran-Iraq conflict between 1983 and 1988(1). SM can cause serious organ damages especially ocular, neurologic, cutaneous, bone marrow, and pulmonary complications (1). The previous studies have shown that the respiratory complications are the most common late com...
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Purpose: To review current knowledge about ocular effects of sulfur mustard (SM) and the associated histopathologic findings and clinical manifestations Methods: Literature review of medical articles (human and animal studies) was accomplished using PubMed, Scopus and ISI databases. A total of 274 relevant articles in English were retrieved and reviewed thoroughly. Results: Eyes are the most se...
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ژورنال
عنوان ژورنال: Inhalation Toxicology
سال: 2010
ISSN: 0895-8378,1091-7691
DOI: 10.3109/08958378.2010.493901